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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0fed1ccb344e7545f7d3e979b063da47fa24da1ae6f8a313575b44ece683b872' 
  AND token = 'DLqTKLz26s4y8bbv1u+qbPsUB4IocfNzvHQ2Se3ev0c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}