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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6189d382abf5700784a3595a5ccf0165614ed8884bc962b05da17470fb5f7745' 
  AND token = '05deU/ZSgNTtYakhzSBTf4zMcTwm3o+Afy6j+eMLckY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}