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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '93e06b363daa647befc38f78f9fc1115ef1ab94fabe7aec62c43404c2e422115' 
  AND token = 'jv7HuWxlXu6A/WeoxE/mAxN0XyBB9xcJDbz2gSe1qlQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}