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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '756baab6358e1474302aefdc75c5bb732ebf14927bf45fa1563f65cc7eb0802e' 
  AND token = 'uEUJHypua4jydb8fGTA/TQZc+RALmyJtEuGy7prFkPQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}