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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7535f407bf58d0f281fb80ba6bfa45c2bd151ad1362418a99961c4c39ad4b703' 
  AND token = 'gMWDhrnaECH26Pf+rb0L1Bfaj6tQfT/44/7TIHImGlc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}