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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d156ccb086e36eb75f3919be13433bc071078f419110e9375db550ed178d8c4' 
  AND token = 's6+YRnTd4KeOPuW15EcpDuqp8C1MYdb1WZY4XTcPd1w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}