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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2131fc6a2c5d4c0c5ded351c4ff31eb524ca316c3bd577ab2a2c65c640016b2' 
  AND token = 'z4TUHB1+7ND0VKfU1t8pBjoM3LCZCi21YjPFa4qk5g0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}