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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d1874923badb9a89497917e5d5e1e13902f28cdf8fc3bc76f1b9a55ccb5a507' 
  AND token = 'MWxZVMAc2vq8xiD67VJryAt3cOJABUMpFJUrbaPeAY4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}