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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53c77815ad4269b73d3ddb8fe1e7f782bf54071b1884f819fabf21e66c488423' 
  AND token = '1eR49Sa1fsEuUWi3GOiM45qWqatHdUufZV5s1gBv+6w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}