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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd65cf825d2a541b4d42709ed148b9b619b68d16f55d4b6a594c6b1caec22a444' 
  AND token = 'pXD3f/O1BHc0it4mh6G5xxu3P86nJ7XDE5XHtZypBS0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}