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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01a2ade2b563d4b2364e6ef6f4b2b0e6ab5f10021a13705f7503743da4c72534' 
  AND token = '0y+Q9RbOoYsk7GbyD0Mc2xsKwlYH5bnqyT278uzSdSc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}