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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2b1cbce07a98cd274c5904706f1a0a709e35cbac73949f49198b5fabcbd922c' 
  AND token = '8lVPYxq/VDb5TNOFc4lWron+C6x5K9kJJZHiHPH5P5o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}