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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3931f4ebe55af5fc13ca186eaaac1c4d1412304d606dab7044d6ddc11adcb89e' 
  AND token = 'uw0MSOPWK7RF0Uu8AodJs/Ubdm4cOgQxijUY27v6Wyc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}