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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '377ebde42c7e64399cf9ef77a5c052a51c3f8f0a65c60dea1dadfc3979dd4201' 
  AND token = '4VhFeU3exlHn07riFE+6h6cDGRc8ScxMYl3sC2alWqM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}