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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10eb65336068166dd9923ece03ef7c1ad9c33ca5a372f07eb6e17f7d36fdf3f9' 
  AND token = 'OrH8gYowfz6zt4I9g8/5UqFF1U+c+hkV8zQCgOrRQZ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}