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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '205e8939703f6f5a23d0e17d7da73bdc76293d153a8dbaecb04b2cc6198b7514' 
  AND token = '8ubT/3iSMulTEMWuKPuR3bCwmVN5rVJ/4d570ZIAOnI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}