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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc22dce166c9dcfdeea2dcd9cc8012d4d302256d71224114120400e61527c6da' 
  AND token = 'VWxeA4jhbhs3B6T6J8WF5advEaqD5wv7/sXPFNrWRTY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}