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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a59f7ab03a3fd501be8d2d7f5b812e7410290f3bd3482c8c8b61214cd8a88e3' 
  AND token = 'r9ip+dgy1n3vaVjcYpvI1J1WpCmlYqIRtSeQ4mJeZWo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}