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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad8085b315cfec014972e5742011a49fc93162bbdc21735b7f564a93e4d6be72' 
  AND token = 'Ew23VAOQe2axlMCn6ena4fiFpp0bhdVcAdPGAw6aiIU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}