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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f18a02aabe7441aaea540bc821b6ba709a6d20190e1ab806c47280d1f834188' 
  AND token = '3XHGMocxbEdCkd1TT6nRIE+rhnjJ6Yc/LscU9L7EJ2I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}