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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '336751bd4bdc7775b9f9de85d218c65bad244420101c62eab731cb8082aa10bd' 
  AND token = 'eVMhY0Ksi5KYLUjwmB9wFkJeOhEXAbYAFkmtdDB2Li0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}