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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50d1b5b690cb798d8ed7f19c60b687b625025a927772c9959839e5c147ac1e4f' 
  AND token = '1+TiaJ/tqszj1ZYYh7WNM4mxoNidCIikmZrZ1ILQJTo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}