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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd01151219f268173c98f815a7053b08dace4f747708133ece957f195f7100969' 
  AND token = 'szU2X2flbBZ5ELiPvb+YeeuHO32J2gv5N1Z9vM7Z8mA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}