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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2428fc2140ede14bd93110b9ba8dc84ecc57080271703cf5ae8d57f73a6c18d' 
  AND token = 'OVj0eHvlOD/CQ06fa/6OotrY8o+5JGRx9QdIbN9Ab6U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}