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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '945717635910b0786b60ab563a7584f16ac88610964d3e4a3144c03c2a32242c' 
  AND token = 'E7vPmgmTP8UpsV9+fAYw7yD00LA8Vgm/0GIARVl3Dmk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}