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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0739085ac3997c3ee06acd6bcccc0582ae1dc7dd664db7d16875788c44c06a8a' 
  AND token = 'UoLBAlac7JssF8yW2d1nkSbn9WqE+DY9LfGhJCpGj5A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}