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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43bf4ff70a757748a126c580aa93d3cb0f388584f0b9cf6ebf02180c4d9e379a' 
  AND token = 'vFv7ePPvcfZQ6XxPy6RQ/i3g4vQ4IuNS9+hMabCyLDw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00062

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}