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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21a35e121a4349d501fd95f36311ef6c13734825176f2437a9737c5b21b5441e' 
  AND token = '+ARZ2fpfG0486i4y/+JJo66/n2vLTVGeZ+xfWOn4rvs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}