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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6b8cabdcf22638bd794452045dffbdae247c13c5cb75ca5b386b74ba0dd1ad5' 
  AND token = 'aSjWpJkLc8KJD45qN6QuCiUKh+qRJgy6+vFe54CKbk4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}