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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd7ac5ff124cd15619847cbe565b271145606a9b4b20491d9a9ee8465907c64c9' 
  AND token = '4WBCfDl/kTlw/4SumcxfVi6/uz9xTyy0A3+TaZW+tZM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}