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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '97e7d18acce6d69a35d80b3de31e8bf96a66f527936ccaa2eee1667b23f4b1e3' 
  AND token = 'XizLyZfamIdRL6rW7HaMUsPGiudg4+6nPVuvOqwOiQM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}