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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b67b4ec88c7d32a2fa29c179a41bbf8610ef7c9287f12a659983e8c1e29e59cc' 
  AND token = 'oxoJMrh6lIFbgG9iUj+K9bwSyQuWDm1zubggsCzuGY0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}