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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd3b26fe4cadf8799c01fb9ed8bd9ac68ecaa293f4f567cee980368f13f25740' 
  AND token = 'osD/4LC+Ux0+Puv5wAdKlIvJEilIM5rOf+33h5CmNRQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}