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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a0ecdceee20fd7f1feebe8919da40f8e0bef4181e81da67ca2fa2b14cadddee' 
  AND token = 'JqnWP3ZuUzkH+oFHpo33OvyQfB2NeM6X1u7QyRL8jcw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}