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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e1a163e05d6237777b504f00b40b03e6b4fd33d89b23b75bcec6d30b680476e' 
  AND token = 'Y4dq/VoZp8CMxKb7IccSqcV5vP7ybvj5Mp0avLE+XDM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}