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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '041c4c2d07730d9695bfff92bdd53f12b588f096dd8e4b49b67e891b28de140b' 
  AND token = 'yshC25lumT/1BvV0RbMVWALnGoR9VUTTvqhjr4EUY68=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}