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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b6724f3edc7a1fd5a196eca22294ac4d7d87b75082e7ab2406b6892f9b90f8a' 
  AND token = 'R3PnRs0K5THbqLzcQf2yxnY+9Ma3FF+78I31Ah+BqDQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}