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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '727a334ad1aabbab2020696e95b5963841f723aa8b5c3bd21b52985426a897e0' 
  AND token = 'NsnCCa8RwZ+3aK5NzyGTFLOkgkB1Aa2QFTaXfJxQE6s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}