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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dc9446b6a2b473394c57a3cfb6dbc6c8621c27adb2224be667acc4024f5f3e5b' 
  AND token = '5ibGwuOGaFBnlInOwx0RRntXNJZCux2NDFifi2ecraU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}