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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9753491d43b46c1d5553c286dd63f831803b1ec9e1b74c4ceea7d52602df1a74' 
  AND token = 'HfxhLPc0ArGbuhNa3z9gXRX1pafMxlG2fJnoa6NwrJU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}