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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43119d36f31bd16a631dac6b84e1fef7b3389b0f0e632a96fc40522217ca1a36' 
  AND token = 'Jqxy4PQ9O/6dEGsnfLMqbBiETeoC/0D9WdWyjkqMNVg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}