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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e83b2d279b9d54b2694455f91d7cfc72e2fabae04fe6c9f019690ffed3236689' 
  AND token = '+fj7T6Oeo0wuubg+D1Vy5L6XCHjoIY3gfBpSPCqs1dw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}