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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e6521b0841e1a0d063b9c3c0c919f04b4e958b243d54ca3d7711ea40ed80738' 
  AND token = 'Q/778rboI6dI8v+gQsh2iUhW99W5p42/QpGskurn0YM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}