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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f7fed021c88a1443177f02e366441fc66b4836b17ad3d80e15b161e33c0b5bd' 
  AND token = 'LxjpHRZB8goZk38uT1EWYysz4Yh5C4YotPqjfyMDRy0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}