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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b544e12362d14c8c34de27be417fed9b3faa42f310d7f831a18b90f2640582a1' 
  AND token = 'h9NEGrZc+jpVxEr+mANIxk5LuvnLo5xABix2fWBDZ+Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}