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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2cb9600feea2b1fd788e74374b7fe521e88be17411fb0a254b186046d14b0d4d' 
  AND token = 'jOXKbQ8xxXxE0vY0gXM2gfa9ZR0v0BQlpviN0+L8OdQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}