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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '32e09a91290d0aa7758dfb45889f8e5bd0a1a8eef72912998cda171c0466bc24' 
  AND token = 'izxF93MNtwtt2/kynua0OpQapDk53OSIV0Rz1xHtnjU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}