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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef73ea349b5c0d4cb409e1e7626daa8e93b2fb13e6da5978921becf4e1807574' 
  AND token = 'tU3jlxcCbO+9uY6MAx/twB3IxvHqk4fY5nDkxwFdka0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}