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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '555c82c103850ca1a579cf797993368e0b524016534b3d1598c3988e56889b57' 
  AND token = 'D6f4FfK9z3oG5UJwhEj8EJEYJRpEEH+knJdxMWh2K4c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}