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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67a5b95e767d2843e2237212d05b0cb174000211253746a84cf07deb6d385b2a' 
  AND token = 'yCYGqNRbMjWmvrS5v0eFNcuOffX7xCRJOiBo+MXJx4c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}